Qi Hao, Ph.D.

Visiting Postdoctoral scholar

UCSF Center for Cerebrovascular Research
1001 Potrero Avenue, Box-1371
San Francisco, CA 94110
phone: 415-206-5667
fax: 415-206-8907
email: haoq@anesthesia.ucsf.edu

Education

• Ph.D., Shanghai JiaoTong University, China
  

Research Interests

• Development of mouse model of brain vascular dysplasia
  
• Study the role of bone marrow derived cells in vasculogenesis and vascular remodeling
  
• Study TGF-ß signaling in vascular remodeling
  

Selected Publications

• Wei Zhu, Yongfeng Fan, Qi Hao, Fanxia Shen, Tomoki Hashimoto, Guo-Yuan Yang, Mehdi Gasmi, Raymond T. Bartus, William L. Young, Yongmei Chen. Post-ischemic IGF-1 Gene Transfer Promotes Neurovascular Regeneration after Experimental Stroke. Journal of Cerebral Blood Flow & Metabolism, 2009, in press.
  
  
• Yongmei Chen*, Qi Hao*, Helen Kim, Hua Su, Michael T. Lawton, Nicholas M. Barbaro, Michelle Letarte, S. Ananth Karumanchi, Guo-Yuan Yang, and William L. Young. Soluble endoglin is highly expressed in human brain arteriovenous malformations and modulates aberrant cerebral vascular remodeling in mice. Annual Neurology, 2009, in press. *Authors contributed equally to the manuscript and are listed in alphabetical order.
  
  
• Chanhung Z. Lee, Zheng Xue, Qi Hao, Guo-Yuan Yang, William L. Young. The Role of Nitric Oxide in VEGF-induced Focal Angiogenesis and Matrix Metalloproteinase-9 Activity in the Mouse Brain. Stroke, 2009, in press.
  
  
• Yiqian Zhu, Ileana C. Cuevas, Rodney Allanigue Gabriel, Hua Su, Alexander Fields, Qi Hao, William L. Young, Guo-Yuan Yang, Nancy J. Boudreau. Restoring HOXA5 Expression Inhibits the Growth of Experimental Hemangiomas in the Brain. Journal of Neuropathology and Experimental Neurology, 2009, in press.
  
  
• Qi Hao, Hua Su, Douglas A. Marchuk, Radoslaw Rola, Yongqiang Wang, Weizhong Liu, William L.Young, and Guo-Yuan Yang. Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation. American Journal of Physiology Heart Circ Physiol., 2008, 295: H2250-H2256.
  
  
• Yongfeng Fan, Fanxia Shen, Yongmei Chen, Qi Hao, Weizhong Liu, Hua Su, William L Young, and Guo-Yuan Yang. Overexpression of Netrin-1 Induces Neovascularization in the Adult Mouse Brain. Journal of Cerebral Blood Flow & Metabolism2008, 28:1543-1551.
  
  
• Qi Hao, Jianrong Liu, Rajita Pappu, Hua Su, William L.Young, Guo-Yuan Yang. Contribution of Bone Marrow-Derived Cells Associated With Brain Angiogenesis Is Primarily Through Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology, 2008, 28: 2151-2157.
  
  
• Hua Su, Qi Hao, Fanxia Shen, Yiqian Zhu, Chanhung Lee, William L Young, Guo-Yuan Yang: Development of cerebral microvascular dysplasia model in rodents. Neurochirurgica Supplementum, 2008, 105: 185-189.
  
  
• CE Pedraza, R Monk, J Lei, Qi Hao, Wendy Macklin. Induction of oligodendrocyte precursor differentiation by small molecules. Glia, 2008, 56(12): 1339-1352.
  
  
• Yongfeng Fan, Wei Zhu, Michael Yang, Yiqian Zhu, Fanxia Shen, Qi Hao, William L. Young, Guo-Yuan Yang, Yongmei Chen. Del-1 Gene Transfer Induces Cerebral Angiogenesis in Mice. Brain Research, 2008, Jul 11; 1219:1-7.
  
  
• Wei Zhu, Steve Khachi, Qi Hao, Fanxia Shen, William L. Young, Guo-Yuan Yang, Yongmei Chen. Upregulation of EMMPRIN after Permanent Focal Cerebral Ischemia. Neurochemistry International, 2008, 52(6):1086-91.
  
  
• Qi Hao, Yongmei Chen, Yiqian Zhu, Yongfeng Fan, Dan Palmer, Hua Su, William L. Young, and Guo-Yuan Yang. Neutrophil depletion decreases VEGF-induced focal angiogenesis in the mature mouse brain. Journal of Cerebral Blood Flow & Metabolism. 2007, 27: 1853-1860. (Cover Story)
  
  
• Qin Shi, Qi Hao, Julien Bouissac, Yang Lu, Songjiu Tian, and Bang Luu. Ginsenoside-Rd from Panax notoginseng enhances astrocyte differentiation from neural stem cells. Life Science, 2005, 76:983-995.